Questões Jornalísticas no Mercúrio Português (1663-1667)

Biol. Pharm. Bull. 30(9) 1663—1667 (2007)

of dihydropyrazines (DHPs) such as 2,3-dihydro-5,6-dimethylpyrazine (Me-DHP), which causes DNA strand breakage in the plasmid pBR322. We showed that DHPs inhibit growth and cause mutagenesis in Escherichia coli and that Me-DHP is cytotoxic and genotoxic in E. coli due to the production of radical species in the presence of Cu . Phenyl substituted dihydropyrazines (Ph-DHPs) have much higher DNA ...

Dmd059006 1663..1674

Nuclear factor erythroid 2–related factor 2 (Nrf2) is a transcription factor that positively regulates the expression and activity of cytoprotective genes during periods of oxidative stress. It has previously been shown that some Nrf2 genes are more highly expressed in livers of female than male mice. This could explain previously reported sex-related differences in susceptibility to acetaminop...

Op-brai150094 1667..1678

Optimal phase alignment between oscillatory neural circuits is hypothesized to optimize information flow and enhance system performance. This theory is known as communication-through-coherence. The basal ganglia motor circuit exhibits exaggerated oscillatory and coherent activity patterns in Parkinson’s disease. Such activity patterns are linked to compromised motor system performance as evince...

Robert Hooke's Micrographia of 1665 and 1667.

Bancos de Fala para o Português Brasileiro

Reconhecimento e síntese de fala demandam grandes quantidades de dados para aplicações comerciais. Em inglês americano, existem grandes quantidades de bancos de fala para a produção de modelos acústicos. Isto não é realidade para muitas línguas, incluindo o Português Brasileiro. Este trabalho apresenta o desenvolvimento de dois bancos de fala para reconhecimento com 248 locutores (224 sentenças...